This high-purity Epitalon peptide provides the scientific community with a powerful tool to investigate the fundamental mechanisms of cellular aging. As of 2025, the field of gerontology has transitioned from observing the effects of aging to actively probing its root causes at the molecular level. Epitalon (also known as Epithalon), a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural pineal gland peptide Epithalamin, stands at the forefront of this research. It is most renowned for its studied effects on telomerase, the enzyme responsible for maintaining the protective caps on our chromosomes, offering a direct avenue for research into cellular longevity.
This product is sold exclusively for in-vitro and laboratory research applications. It provides scientists with a compound of exceptional purity and stability, which is essential for generating reproducible and conclusive data in the complex and promising field of anti-aging science.
The Scientific Significance of Our High-Purity Epitalon Peptide
The validity of any advanced biological research hinges on the quality of the compounds used. Our commitment is to provide a high-purity Epitalon peptide that meets the exacting standards required for sensitive cellular assays and long-term studies, allowing researchers to explore its multifaceted biological activities with confidence.
The Core Mechanism: Investigating Telomerase Activation
The most significant area of Epitalon research is its relationship with telomeres.
Understanding Telomeres: Telomeres are sequences of DNA at the ends of chromosomes that protect them from degradation. With each cell division, these telomeres naturally shorten, a process that is considered a key hallmark of cellular aging. Once telomeres become critically short, the cell enters a state of senescence or undergoes apoptosis.
The Role of Telomerase: Telomerase is a specialized enzyme that can add DNA to the ends of telomeres, thereby counteracting their progressive shortening.
Epitalon in Research: Our high-purity Epitalon peptide is a critical tool for scientists studying the regulation of this enzyme. In various preclinical and in-vitro models, Epitalon has been shown to activate the gene encoding for telomerase, leading to telomere elongation. This makes it an invaluable compound for research into slowing cellular senescence and understanding the mechanics of cellular lifespan extension.
Pineal Gland Regulation and Circadian Rhythms
Epitalon’s origins are tied to the pineal gland, the body’s master regulator of circadian rhythms. As a result, it is also a key compound for studying the relationship between the sleep-wake cycle and aging. Research applications in this area include:
Melatonin Secretion: Investigating Epitalon’s ability to normalize the age-related decline in melatonin production by the pineal gland.
Circadian Rhythm Restoration: Studying its potential to restore and maintain healthy sleep-wake cycles, which are often disrupted during the aging process and are crucial for overall physiological health.
Antioxidant and Geroprotective Research
Beyond its effects on telomerase, this peptide is also a subject of study for its broader geroprotective (anti-aging) properties. Scientists use our high-purity Epitalon peptide to explore:
Antioxidant Activity: Its ability to upregulate endogenous antioxidant enzymes and scavenge free radicals, thereby reducing the burden of oxidative stress, another major contributor to the aging process.
Gene Regulation: Research into its influence on the expression of various genes related to cellular repair and function.
Guaranteed Purity for Reproducible Gerontology Studies
Long-term aging studies demand absolute consistency. We ensure this through:
Precise Synthesis: Building the exact Ala-Glu-Asp-Gly tetrapeptide sequence with cutting-edge synthesis technology.
HPLC Verification: Using high-performance liquid chromatography to purify every batch to a standard of >99%, removing any contaminants or incomplete sequences.
Mass Spectrometry Confirmation: Verifying the precise molecular weight and identity of the peptide.
Lyophilization for Longevity: Supplying the peptide in a stable, freeze-dried form to ensure its integrity and a long shelf-life.
FAQs (Frequently Asked Questions)
What is Epitalon (Epithalon)?
Epitalon, also known as Epithalon, is a synthetic tetrapeptide (composed of four amino acids). It is a research compound based on a natural peptide found in the pineal gland and is primarily studied in the field of gerontology for its effects on cellular aging.
What is the primary mechanism of action studied for Epitalon?
The most researched mechanism is its ability to activate the enzyme telomerase. This enzyme helps maintain the length of telomeres, the protective caps at the ends of chromosomes, which is a key area of study in anti-aging science.
What is the purity of your peptide, and how do you verify it?
Our high-purity Epitalon peptide is guaranteed to be >99% pure. We verify this for every batch using High-Performance Liquid Chromatography (HPLC) and confirm its identity with Mass Spectrometry (MS). A Certificate of Analysis (COA) is available.
What is the amino acid sequence of Epitalon?
The amino acid sequence is Alanine-Glutamic acid-Aspartic acid-Glycine, or Ala-Glu-Asp-Gly.
What are the recommended storage and handling protocols?
The lyophilized (freeze-dried) powder should be stored in a freezer at -20°C for maximum stability. After reconstitution with sterile bacteriostatic water, the solution should be stored in a refrigerator at 2-8°C.
Is this product intended for human use or anti-aging treatments?
Absolutely not. This product is a chemical for laboratory research only. It is not a medication, supplement, or cosmetic and has not been approved for any human or veterinary application. Its use is strictly limited to in-vitro studies and laboratory experimentation.
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